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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase ITK/TSK' and Ligand = 'BDBM50331258'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ITK/TSK


(Homo sapiens (Human))		BDBM50331258
PNG
(3-(5-methoxy-1H-indol-2-yl)-1H-indazole | CHEMBL12...)
Show SMILES COc1ccc2[nH]c(cc2c1)-c1n[nH]c2ccccc12
Show InChI InChI=1S/C16H13N3O/c1-20-11-6-7-13-10(8-11)9-15(17-13)16-12-4-2-3-5-14(12)18-19-16/h2-9,17H,1H3,(H,18,19)
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MMDB

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n/an/a 120n/an/an/an/an/an/a



Nycomed GmbH

Curated by ChEMBL


Assay Description
Inhibition of recombinant GST- tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assay

Bioorg Med Chem Lett 20: 6998-7003 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.119
BindingDB Entry DOI: 10.7270/Q2JD4X29
More data for this
Ligand-Target Pair