Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM159773'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM159773 (US10966980, Example 27 | US9035074, 27) Show SMILES CN([C@@H]1C[C@@H](C1)NS(=O)(=O)N1C[C@@H]2C[C@@]2(C1)C#N)c1ncnc2[nH]ccc12 |r,wU:12.13,wD:2.1,4.6,14.18,(-6.58,1.48,;-5.25,.71,;-3.92,1.48,;-3.52,2.97,;-2.03,2.57,;-2.43,1.09,;-.7,3.34,;.64,2.57,;-.13,1.24,;1.41,3.91,;1.97,1.8,;2.13,.27,;3.64,-.05,;5.18,-.05,;4.41,1.28,;3.38,2.43,;5.5,2.37,;6.58,3.46,;-5.25,-.83,;-6.58,-1.6,;-6.58,-3.14,;-5.25,-3.91,;-3.92,-3.14,;-2.45,-3.61,;-1.55,-2.37,;-2.45,-1.12,;-3.92,-1.6,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...				US Patent US10966980 (2021) BindingDB Entry DOI: 10.7270/Q29S1V59
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK1 (Homo sapiens (Human))	BDBM159773 (US10966980, Example 27 | US9035074, 27) Show SMILES CN([C@@H]1C[C@@H](C1)NS(=O)(=O)N1C[C@@H]2C[C@@]2(C1)C#N)c1ncnc2[nH]ccc12 |r,wU:12.13,wD:2.1,4.6,14.18,(-6.58,1.48,;-5.25,.71,;-3.92,1.48,;-3.52,2.97,;-2.03,2.57,;-2.43,1.09,;-.7,3.34,;.64,2.57,;-.13,1.24,;1.41,3.91,;1.97,1.8,;2.13,.27,;3.64,-.05,;5.18,-.05,;4.41,1.28,;3.38,2.43,;5.5,2.37,;6.58,3.46,;-5.25,-.83,;-6.58,-1.6,;-6.58,-3.14,;-5.25,-3.91,;-3.92,-3.14,;-2.45,-3.61,;-1.55,-2.37,;-2.45,-1.12,;-3.92,-1.6,)| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	25
Pfizer Inc. US Patent					Assay Description Test article and assay controls were added to a 384-well plate. Reaction mixtures contained 20 mM HEPES, pH 7.4, 10 mM magnesium chloride, 0.01% bovi...				US Patent US9035074 (2015) BindingDB Entry DOI: 10.7270/Q26H4G56
					More data for this Ligand-Target Pair