Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM214689 (US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a |
Arromax Pharmatech Co. Ltd. Curated by ChEMBL | Assay Description Inhibition of JAK2 (unknown origin) assessed as dissociate constant | Eur J Med Chem 170: 55-72 (2019) Article DOI: 10.1016/j.ejmech.2019.03.004 BindingDB Entry DOI: 10.7270/Q2474F5D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM214689 (US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a | 25 |
Ambit Biosciences Corporation US Patent | Assay Description For the binding assays, streptavidin-coated magnetic beads were treated with biotinylated affinity ligands for 30 min at room temperature to generate... | US Patent US9295672 (2016) BindingDB Entry DOI: 10.7270/Q2ZP44ZX | |||||||||||
More data for this Ligand-Target Pair |