Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM332981'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM332981 (US10196390, Compound I-270) Show SMILES O[C@H]1CCCN(C1)c1ccc(Nc2cc(nc3CNC(=O)c23)-c2c(F)cccc2F)nc1 |r| Show InChI InChI=1S/C23H21F2N5O2/c24-15-4-1-5-16(25)21(15)17-9-18(22-19(28-17)11-27-23(22)32)29-20-7-6-13(10-26-20)30-8-2-3-14(31)12-30/h1,4-7,9-10,14,31H,2-3,8,11-12H2,(H,27,32)(H,26,28,29)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Nimbus Lakshmi, Inc. US Patent									US Patent US10196390 (2019) BindingDB Entry DOI: 10.7270/Q22809Q4
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