Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50094616'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50094616 (CHEMBL3589325) Show SMILES CN1CCN(CC1)c1ccc2c(c1)[nH]c1c(cc(cc21)-c1ccccc1)C(N)=O Show InChI InChI=1S/C24H24N4O/c1-27-9-11-28(12-10-27)18-7-8-19-20-13-17(16-5-3-2-4-6-16)14-21(24(25)29)23(20)26-22(19)15-18/h2-8,13-15,26H,9-12H2,1H3,(H2,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin)				Bioorg Med Chem Lett 25: 2809-12 (2015) Article DOI: 10.1016/j.bmcl.2015.04.101 BindingDB Entry DOI: 10.7270/Q2BC419G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50094616 (CHEMBL3589325) Show SMILES CN1CCN(CC1)c1ccc2c(c1)[nH]c1c(cc(cc21)-c1ccccc1)C(N)=O Show InChI InChI=1S/C24H24N4O/c1-27-9-11-28(12-10-27)18-7-8-19-20-13-17(16-5-3-2-4-6-16)14-21(24(25)29)23(20)26-22(19)15-18/h2-8,13-15,26H,9-12H2,1H3,(H2,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibition of JAK2 in human SET2 cells assessed as inhibition of cell proliferation				Bioorg Med Chem Lett 25: 2809-12 (2015) Article DOI: 10.1016/j.bmcl.2015.04.101 BindingDB Entry DOI: 10.7270/Q2BC419G
					More data for this Ligand-Target Pair