BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50313807'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50313807 (CHEMBL1093749 \| N-methyl-4-(3-(3,4,5-trimethoxyphe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant GST tagged JAK2 after 60 mins by Caliper mobility shift assay				Bioorg Med Chem Lett 20: 1858-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.151 BindingDB Entry DOI: 10.7270/Q2PR7W4M
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50313807 (CHEMBL1093749 \| N-methyl-4-(3-(3,4,5-trimethoxyphe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant GST tagged JAK2 protein after 60 mins using FITC-GGEEEEYFELVKKKK-NH2 substrate				Bioorg Med Chem Lett 20: 2609-13 (2010) Article DOI: 10.1016/j.bmcl.2010.02.056 BindingDB Entry DOI: 10.7270/Q2862GKB
					More data for this Ligand-Target Pair				3D Structure (crystal)