Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50433615'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50433615 (CHEMBL2381976) Show SMILES C[C@H](Nc1nc(Nc2cc(C)n[nH]2)nc(N2CCNCC2)c1F)c1ccc(F)cn1 |r| Show InChI InChI=1S/C19H23F2N9/c1-11-9-15(29-28-11)25-19-26-17(24-12(2)14-4-3-13(20)10-23-14)16(21)18(27-19)30-7-5-22-6-8-30/h3-4,9-10,12,22H,5-8H2,1-2H3,(H3,24,25,26,27,28,29)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of JAK2 (unknown origin) using biotinylated TYK2 peptide as substrate after 60 mins				Bioorg Med Chem Lett 23: 3105-10 (2013) Article DOI: 10.1016/j.bmcl.2013.02.111 BindingDB Entry DOI: 10.7270/Q23T9JMX
					More data for this Ligand-Target Pair