Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50095964'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50095964 (CHEMBL3593765) Show SMILES NC(=O)c1cnc2[nH]ccc2c1NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19N7O4/c1-2-22-18(29)15-13(27)14(28)19(30-15)26-9-23-12-16(20)24-11(25-17(12)26)6-5-10-4-3-7-21-8-10/h3-4,7-9,13-15,19,27-28H,2H2,1H3,(H,22,29)(H2,20,24,25)/t13-,14+,15+,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant JAK3 (unknown origin) using GFP-STAT1 as substrate incubated for 1 hr followed by anti-pSTAT1 antibody addition and measure...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01026 BindingDB Entry DOI: 10.7270/Q2W95DTD
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Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50095964 (CHEMBL3593765) Show SMILES NC(=O)c1cnc2[nH]ccc2c1NC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19N7O4/c1-2-22-18(29)15-13(27)14(28)19(30-15)26-9-23-12-16(20)24-11(25-17(12)26)6-5-10-4-3-7-21-8-10/h3-4,7-9,13-15,19,27-28H,2H2,1H3,(H,22,29)(H2,20,24,25)/t13-,14+,15+,19?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human JAK3 kinase domain using biotin-Lyn-substrate-2 as substrate incubated for 1 hr by ELISA method				Bioorg Med Chem 23: 4871-83 (2015) Article DOI: 10.1016/j.bmc.2015.05.034 BindingDB Entry DOI: 10.7270/Q2DZ0B21
					More data for this Ligand-Target Pair