Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM4301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM4301 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...) Show SMILES NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of p56 lck tyrosine kinase				Bioorg Med Chem Lett 1: 165-168 (1991) Article DOI: 10.1016/S0960-894X(01)80792-7 BindingDB Entry DOI: 10.7270/Q2WH2PWJ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM4301 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...) Show SMILES NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Ability to inhibit autophosphorylation of immunopurified p56Ick				J Med Chem 36: 425-32 (1993) BindingDB Entry DOI: 10.7270/Q2CV4GTQ
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM4301 ((2E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide...) Show SMILES NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N Show InChI InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Ability to inhibit autophosphorylation of immunopurified p56Ick				J Med Chem 36: 425-32 (1993) BindingDB Entry DOI: 10.7270/Q2CV4GTQ
					More data for this Ligand-Target Pair