Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50112948'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112948 ((4-(2-chloro-6-methylphenylamino)-6,7-dimethoxyimi...) Show SMILES COc1ccc2c(nc(Nc3c(C)cccc3Cl)c3cnc(CO)n23)c1OC Show InChI InChI=1S/C20H19ClN4O3/c1-11-5-4-6-12(21)17(11)23-20-14-9-22-16(10-26)25(14)13-7-8-15(27-2)19(28-3)18(13)24-20/h4-9,26H,10H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50112948 ((4-(2-chloro-6-methylphenylamino)-6,7-dimethoxyimi...) Show SMILES COc1ccc2c(nc(Nc3c(C)cccc3Cl)c3cnc(CO)n23)c1OC Show InChI InChI=1S/C20H19ClN4O3/c1-11-5-4-6-12(21)17(11)23-20-14-9-22-16(10-26)25(14)13-7-8-15(27-2)19(28-3)18(13)24-20/h4-9,26H,10H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against recombinant p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells using a baculovirus expression syst...				Bioorg Med Chem Lett 12: 1361-4 (2002) BindingDB Entry DOI: 10.7270/Q2R78DJ1
					More data for this Ligand-Target Pair