Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50116409'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50116409 (2-(2-Chloro-6-methyl-phenylamino)-6,6-dimethyl-1,6...) Show SMILES Cc1cccc(Cl)c1Nc1nc2ccc3c(C(=O)NC(=O)C3(C)C)c2[nH]1 Show InChI InChI=1S/C19H17ClN4O2/c1-9-5-4-6-11(20)14(9)22-18-21-12-8-7-10-13(15(12)23-18)16(25)24-17(26)19(10,2)3/h4-8H,1-3H3,(H2,21,22,23)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human p56 Lck tyrosine kinase				J Med Chem 45: 3394-405 (2002) BindingDB Entry DOI: 10.7270/Q2CJ8CTW
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