Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50118658'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50118658 (Ac-YAEIE | CHEMBL90294) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O Show InChI InChI=1S/C30H43N5O12/c1-5-15(2)25(29(45)34-21(30(46)47)11-13-24(40)41)35-27(43)20(10-12-23(38)39)33-26(42)16(3)31-28(44)22(32-17(4)36)14-18-6-8-19(37)9-7-18/h6-9,15-16,20-22,25,37H,5,10-14H2,1-4H3,(H,31,44)(H,32,36)(H,33,42)(H,34,45)(H,35,43)(H,38,39)(H,40,41)(H,46,47)/t15-,16-,20-,21-,22-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mogam Biotechnology Research Institute Curated by ChEMBL					Assay Description Affinity for GST-Lck-SH2 domain in ELISA				Bioorg Med Chem Lett 12: 2711-4 (2002) BindingDB Entry DOI: 10.7270/Q2H131C3
					More data for this Ligand-Target Pair