Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50120097'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120097 ((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...) Show SMILES COc1cc2nc(Nc3c(C)cccc3C)c3cncn3c2cc1OC Show InChI InChI=1S/C20H20N4O2/c1-12-6-5-7-13(2)19(12)23-20-16-10-21-11-24(16)15-9-18(26-4)17(25-3)8-14(15)22-20/h5-11H,1-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description 50% inhibition of the phosphorylation of an exogenous substrate by human Lck enzyme.				Bioorg Med Chem Lett 12: 3153-6 (2002) BindingDB Entry DOI: 10.7270/Q2NC60JR
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120097 ((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...) Show SMILES COc1cc2nc(Nc3c(C)cccc3C)c3cncn3c2cc1OC Show InChI InChI=1S/C20H20N4O2/c1-12-6-5-7-13(2)19(12)23-20-16-10-21-11-24(16)15-9-18(26-4)17(25-3)8-14(15)22-20/h5-11H,1-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
University of Zurich Curated by ChEMBL					Assay Description Inhibition of Lck				J Med Chem 51: 1179-88 (2008) Article DOI: 10.1021/jm070654j BindingDB Entry DOI: 10.7270/Q29Z95RD
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50120097 ((7,8-Dimethoxy-imidazo[1,5-a]quinoxalin-4-yl)-(2,6...) Show SMILES COc1cc2nc(Nc3c(C)cccc3C)c3cncn3c2cc1OC Show InChI InChI=1S/C20H20N4O2/c1-12-6-5-7-13(2)19(12)23-20-16-10-21-11-24(16)15-9-18(26-4)17(25-3)8-14(15)22-20/h5-11H,1-4H3,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Evaluated for inhibition of human p56 Lck tyrosine kinase				J Med Chem 47: 2534-49 (2004) Article DOI: 10.1021/jm0304358 BindingDB Entry DOI: 10.7270/Q2KH0P3P
					More data for this Ligand-Target Pair