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Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase Lck' and Ligand = 'BDBM50135404'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50135404
PNG
(2-(Cyclopropanecarbonyl-amino)-thiazole-5-carboxyl...)
Show SMILES Cc1cc(C)c(NC(=O)c2cnc(NC(=O)C3CC3)s2)c(C)c1
Show InChI InChI=1S/C17H19N3O2S/c1-9-6-10(2)14(11(3)7-9)19-16(22)13-8-18-17(23-13)20-15(21)12-4-5-12/h6-8,12H,4-5H2,1-3H3,(H,19,22)(H,18,20,21)
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n/an/a 18n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound human Lck(hLck) kinase

Bioorg Med Chem Lett 13: 4007-10 (2003)


BindingDB Entry DOI: 10.7270/Q2CC103J
More data for this
Ligand-Target Pair