Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase Lyn (Homo sapiens (Human)) | BDBM1773 (US10280174, Comparative Compound 1 | US8476284, 4 ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | US Patent | 14 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Pharmacyclics, Inc. US Patent | Assay Description Btk kinase activity was determined using a time-resolved fluorescence resonance energy transfer (TR-FRET) methodology. | US Patent US8476284 (2013) BindingDB Entry DOI: 10.7270/Q2CJ8C3G | |||||||||||
More data for this Ligand-Target Pair |