Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase SYK (Homo sapiens (Human)) | BDBM182770 (US9145414, 26) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | 7.5 | 25 |
TAIHO PHARMACEUTICAL CO., LTD. US Patent | Assay Description The in vitro inhibitory activity of the compound of the present invention against Syk kinase activity was assayed under the following conditions: the... | US Patent US9145414 (2015) BindingDB Entry DOI: 10.7270/Q2513X18 | |||||||||||
More data for this Ligand-Target Pair |