Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM291001'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM291001 ((R)-2-(2-amino-3-methoxypropylamino)-4-(2,3-dihydr...) Show SMILES COC[C@H](N)CNc1ncc(C(N)=O)c(Nc2cccc3n4CCCc4cc23)n1 |r| Show InChI InChI=1S/C20H25N7O2/c1-29-11-12(21)9-23-20-24-10-15(18(22)28)19(26-20)25-16-5-2-6-17-14(16)8-13-4-3-7-27(13)17/h2,5-6,8,10,12H,3-4,7,9,11,21H2,1H3,(H2,22,28)(H2,23,24,25,26)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.5	25
Portola Pharmaceuticals, Inc. US Patent					Assay Description Potency of candidate molecules for inhibiting syk tyrosine phosphorylation activity is assessed by measuring the ability of a test compound to inhibi...				US Patent US9579320 (2017) BindingDB Entry DOI: 10.7270/Q2K07692
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