Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 1' and Ligand = 'BDBM50113295'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50113295 (1-[5-(4-Chloro-phenyl)-2-phenyl-2H-pyrazol-3-yl]-3...) Show SMILES Clc1ccc(cc1)-c1cc(NC(=O)Nc2ccccc2)n(n1)-c1ccccc1 Show InChI InChI=1S/C22H17ClN4O/c23-17-13-11-16(12-14-17)20-15-21(27(26-20)19-9-5-2-6-10-19)25-22(28)24-18-7-3-1-4-8-18/h1-15H,(H2,24,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Protein-tyrosine phosphatase 1B (PTP1B) dephosphorylation of insulin receptor peptide				J Med Chem 45: 2213-21 (2002) BindingDB Entry DOI: 10.7270/Q2SB46F1
					More data for this Ligand-Target Pair