Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 9 [277-582]' and Ligand = 'BDBM231166'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 9 [277-582] (Homo sapiens (Human))	BDBM231166 (US9340574, 5) Show SMILES Cc1ccc(cc1Br)C(=O)NC(Cc1ccc(cc1)C(F)(F)P(O)(O)=O)C(=O)NC(CCCNC(=O)c1cccc(I)c1)C(N)=O Show InChI InChI=1S/C30H31BrF2IN4O7P/c1-17-7-10-20(16-23(17)31)28(41)38-25(14-18-8-11-21(12-9-18)30(32,33)46(43,44)45)29(42)37-24(26(35)39)6-3-13-36-27(40)19-4-2-5-22(34)15-19/h2,4-5,7-12,15-16,24-25H,3,6,13-14H2,1H3,(H2,35,39)(H,36,40)(H,37,42)(H,38,41)(H2,43,44,45)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	7.0	n/a
Indiana University Research and Technology Corporation US Patent					Assay Description PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...				US Patent US9340574 (2016) BindingDB Entry DOI: 10.7270/Q2NV9H4J
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