Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uracil-DNA glycosylase (Homo sapiens (Human)) | BDBM36455 (6-[4-[(3-Carboxybenzylamino)butylamino]methyl]urac...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | n/a | n/a | 3.15E+5 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Johns Hopkins University | Assay Description Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate. | Nat Chem Biol 5: 407-13 (2009) Article DOI: 10.1038/nchembio.163 BindingDB Entry DOI: 10.7270/Q2W37TP8 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |