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Found 1 hit Enz. Inhib. hit(s) with Target = 'Uracil-DNA glycosylase' and Ligand = 'BDBM50343403'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343403
PNG
(4-methoxy-N-(1-(2-(4-methoxyphenoxy)ethyl)-1H-benz...)
Show SMILES COc1ccc(OCCn2c(NC(=O)c3ccc(OC)cc3)nc3ccccc23)cc1
Show InChI InChI=1S/C24H23N3O4/c1-29-18-9-7-17(8-10-18)23(28)26-24-25-21-5-3-4-6-22(21)27(24)15-16-31-20-13-11-19(30-2)12-14-20/h3-14H,15-16H2,1-2H3,(H,25,26,28)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.69E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair