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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Urotensin-2 receptor' and Ligand = 'BDBM50252312'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urotensin-2 receptor


(Homo sapiens (Human))		BDBM50252312
PNG
(CHEMBL482302 | N-(1-(3-bromo-4-(piperidin-4-yloxy)...)
Show SMILES Clc1ccc(cc1Cl)C(=O)NC1CCN(CC1)S(=O)(=O)c1ccc(OC2CCNCC2)c(Br)c1
Show InChI InChI=1S/C23H26BrCl2N3O4S/c24-19-14-18(2-4-22(19)33-17-5-9-27-10-6-17)34(31,32)29-11-7-16(8-12-29)28-23(30)15-1-3-20(25)21(26)13-15/h1-4,13-14,16-17,27H,5-12H2,(H,28,30)
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 140n/an/an/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant urotensin 2 receptor expressed in HEK293 cells assessed as inhibition of urotensin 2-induced calcium mobiliz...

Bioorg Med Chem Lett 18: 3950-4 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.019
BindingDB Entry DOI: 10.7270/Q2FT8KTR
More data for this
Ligand-Target Pair