Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' and Ligand = 'BDBM107697'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107697 (US8598210, Table XV, 3 | US8722895, 3: {[5-(4-Cyan...) Show SMILES COC(=O)CNC(=O)c1ncc(cc1O)-c1ccc(cc1)[N+]#[C-] Show InChI InChI=1S/C16H13N3O4/c1-17-12-5-3-10(4-6-12)11-7-13(20)15(18-8-11)16(22)19-9-14(21)23-2/h3-8,20H,9H2,2H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Akebia Therapeutics, Inc. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US8598210 (2013) BindingDB Entry DOI: 10.7270/Q2M04428
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