Reaction Details |
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Target | Vascular endothelial growth factor A |
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Ligand | BDBM107697 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ELISA Assay |
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EC50 | >1.00e+5±n/a nM |
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Citation | Kawamoto, RM; Wu, S; Warshakoon, NC; Evdokimov, AG; Greis, KD; Boyer, AS Prolyl hydroxylase inhibitors and methods of use US Patent US8598210 Publication Date 12/3/2013 |
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More Info.: | Get all data from this article, Assay Method |
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Vascular endothelial growth factor A |
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Name: | Vascular endothelial growth factor A |
Synonyms: | VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor |
Type: | Protein |
Mol. Mass.: | 27063.81 |
Organism: | Homo sapiens (Human) |
Description: | P15692 |
Residue: | 395 |
Sequence: | MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLG
CSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWT
GEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASET
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
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BDBM107697 |
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n/a |
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Name | BDBM107697 |
Synonyms: | US8598210, Table XV, 3 | US8722895, 3: {[5-(4-Cyano-phenyl)-3-hydroxy-pyridine-2- carbonyl]-amino}-acetic acid methyl ester |
Type | Small organic molecule |
Emp. Form. | C16H13N3O4 |
Mol. Mass. | 311.2921 |
SMILES | COC(=O)CNC(=O)c1ncc(cc1O)-c1ccc(cc1)[N+]#[C-] |
Structure |
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