Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A' and Ligand = 'BDBM107716'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107716 (US11426393, Compound Table XV.22 | US8598210, Tabl...) Show SMILES COC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)C(=O)N1CCCC1 Show InChI InChI=1S/C20H21N3O5/c1-28-17(25)12-22-19(26)18-16(24)10-15(11-21-18)13-5-4-6-14(9-13)20(27)23-7-2-3-8-23/h4-6,9-11,24H,2-3,7-8,12H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Akebia Therapeutics, Inc. US Patent					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				US Patent US8598210 (2013) BindingDB Entry DOI: 10.7270/Q2M04428
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107716 (US11426393, Compound Table XV.22 | US8598210, Tabl...) Show SMILES COC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)C(=O)N1CCCC1 Show InChI InChI=1S/C20H21N3O5/c1-28-17(25)12-22-19(26)18-16(24)10-15(11-21-18)13-5-4-6-14(9-13)20(27)23-7-2-3-8-23/h4-6,9-11,24H,2-3,7-8,12H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
University of California at Los Angeles					Assay Description HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...				Bioorg Med Chem 17: 7174-85 (2009) BindingDB Entry DOI: 10.7270/Q2D50Q9S
					More data for this Ligand-Target Pair
Vascular endothelial growth factor A (Homo sapiens (Human))	BDBM107716 (US11426393, Compound Table XV.22 | US8598210, Tabl...) Show SMILES COC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)C(=O)N1CCCC1 Show InChI InChI=1S/C20H21N3O5/c1-28-17(25)12-22-19(26)18-16(24)10-15(11-21-18)13-5-4-6-14(9-13)20(27)23-7-2-3-8-23/h4-6,9-11,24H,2-3,7-8,12H2,1H3,(H,22,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
Akebia Therapeutics, Inc. US Patent									US Patent US9598370 (2017) BindingDB Entry DOI: 10.7270/Q20G3N64
					More data for this Ligand-Target Pair