| Reaction Details |
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 | Report a problem with these data |
| Target | Vascular endothelial growth factor A |
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| Ligand | BDBM107716 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ELISA Assay |
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| EC50 | >1.00e+5±n/a nM |
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| Citation |  Kawamoto, RM; Wu, S; Warshakoon, NC; Evdokimov, AG; Greis, KD; Boyer, AS Prolyl hydroxylase inhibitors and methods of use US Patent US8598210 Publication Date 12/3/2013 |
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| More Info.: | Get all data from this article, Assay Method |
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| Vascular endothelial growth factor A |
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| Name: | Vascular endothelial growth factor A |
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| Synonyms: | VEGF | VEGF-A | VEGFA | VEGFA_HUMAN | VPF | Vascular endothelial growth factor (VEGF) | Vascular endothelial growth factor A (VEGF) | Vascular endothelial growth factor A (VEGF2) | Vascular permeability factor |
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| Type: | Protein |
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| Mol. Mass.: | 27063.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P15692 |
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| Residue: | 395 |
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| Sequence: | MTDRQTDTAPSPSYHLLPGRRRTVDAAASRGQGPEPAPGGGVEGVGARGVALKLFVQLLG
CSRFGGAVVRAGEAEPSGAARSASSGREEPQPEEGEEEEEKEEERGPQWRLGARKPGSWT
GEAAVCADSAPAARAPQALARASGRGGRVARRGAEESGPPHSPSRRGSASRAGPGRASET
MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVD
IFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEM
SFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVPCGPCSERRKHLFVQ
DPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
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| BDBM107716 |
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| n/a |
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| Name | BDBM107716 |
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| Synonyms: | US11426393, Compound Table XV.22 | US8598210, Table XV, 22 | US8722895, 22: ({3-Hydroxy-5-[3-(pyrrolidine-1-carbonyl)- phenyl]-pyridine-2-carbonyl}-amino)-acetic acid methyl ester | US9598370, Example 00147 | USRE47437, Example ({3-Hydroxy-5-[3-(pyrrolidine-1-carbonyl)-phenyl]-pyridine-2-carbonyl}-amino)-aceticacid methyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21N3O5 |
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| Mol. Mass. | 383.3978 |
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| SMILES | COC(=O)CNC(=O)c1ncc(cc1O)-c1cccc(c1)C(=O)N1CCCC1 |
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| Structure | 
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