Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM139624'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139624 (US8889870, 172 | US9388176, 172 | US9820989, 172) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(=O)NCCCN2CCOCC2)c1 Show InChI InChI=1S/C32H39N5O3/c1-23(2)24-6-3-8-27(18-24)35-31(38)25-7-4-9-28(19-25)37-13-10-29-26(22-37)20-33-21-30(29)32(39)34-11-5-12-36-14-16-40-17-15-36/h3-4,6-9,18-21,23H,5,10-17,22H2,1-2H3,(H,34,39)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	367	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...				US Patent US9820989 (2017) BindingDB Entry DOI: 10.7270/Q2TT4T6G
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139624 (US8889870, 172 | US9388176, 172 | US9820989, 172) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(=O)NCCCN2CCOCC2)c1 Show InChI InChI=1S/C32H39N5O3/c1-23(2)24-6-3-8-27(18-24)35-31(38)25-7-4-9-28(19-25)37-13-10-29-26(22-37)20-33-21-30(29)32(39)34-11-5-12-36-14-16-40-17-15-36/h3-4,6-9,18-21,23H,5,10-17,22H2,1-2H3,(H,34,39)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	367	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 .mu.g/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US8889870 (2014) BindingDB Entry DOI: 10.7270/Q25B0158
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM139624 (US8889870, 172 | US9388176, 172 | US9820989, 172) Show SMILES CC(C)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cncc3C(=O)NCCCN2CCOCC2)c1 Show InChI InChI=1S/C32H39N5O3/c1-23(2)24-6-3-8-27(18-24)35-31(38)25-7-4-9-28(19-25)37-13-10-29-26(22-37)20-33-21-30(29)32(39)34-11-5-12-36-14-16-40-17-15-36/h3-4,6-9,18-21,23H,5,10-17,22H2,1-2H3,(H,34,39)(H,35,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	367	n/a	n/a	n/a	n/a	7.4	30
ALLERGAN, INC. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microliter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...				US Patent US9388176 (2016) BindingDB Entry DOI: 10.7270/Q2TQ60DZ
					More data for this Ligand-Target Pair