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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50245291'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))		BDBM50245291
PNG
(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-pheny...)
Show SMILES COc1cc2nccc(Oc3ccc4c(Nc5ccccc5)nn(C)c4c3)c2cc1OC
Show InChI InChI=1S/C25H22N4O3/c1-29-21-13-17(9-10-18(21)25(28-29)27-16-7-5-4-6-8-16)32-22-11-12-26-20-15-24(31-3)23(30-2)14-19(20)22/h4-15H,1-3H3,(H,27,28)
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Amgen, Inc.

Curated by ChEMBL


Assay Description
Inhibition of recombinant KDR by HTRF assay

Bioorg Med Chem Lett 18: 4844-8 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.080
BindingDB Entry DOI: 10.7270/Q2W9591V
More data for this
Ligand-Target Pair