Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50277281'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50277281 (4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1 Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) at IC90 concentration by ATP based competition assay				Bioorg Med Chem Lett 19: 1195-8 (2009) Article DOI: 10.1016/j.bmcl.2008.12.078 BindingDB Entry DOI: 10.7270/Q2W66KNK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50277281 (4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1 Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) at IC50 concentration by ATP based competition assay				Bioorg Med Chem Lett 19: 1195-8 (2009) Article DOI: 10.1016/j.bmcl.2008.12.078 BindingDB Entry DOI: 10.7270/Q2W66KNK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50277281 (4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1 Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assay				Bioorg Med Chem Lett 19: 1195-8 (2009) Article DOI: 10.1016/j.bmcl.2008.12.078 BindingDB Entry DOI: 10.7270/Q2W66KNK
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50277281 (4-(pyridin-4-ylmethylamino)-N-(3-(trifluoromethyl)...) Show SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCc2ccncc2)c1 Show InChI InChI=1S/C17H13F3N4OS/c18-17(19,20)12-2-1-3-13(8-12)23-16(25)15-14(10-26-24-15)22-9-11-4-6-21-7-5-11/h1-8,10,22H,9H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISA				Bioorg Med Chem Lett 19: 1195-8 (2009) Article DOI: 10.1016/j.bmcl.2008.12.078 BindingDB Entry DOI: 10.7270/Q2W66KNK
					More data for this Ligand-Target Pair