BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'Vasopressin V2 receptor' and Ligand = 'BDBM35667'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 301-8 (1997) BindingDB Entry DOI: 10.7270/Q25T3J1N
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	0.950	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Second Tokushima Institute of New Drug Research Curated by PDSP K_i Database									J Pharmacol Exp Ther 287: 860-7 (1998) BindingDB Entry DOI: 10.7270/Q2S46QGC
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cells after 30 mins by saturation binding assay				J Med Chem 55: 8588-602 (2012) Article DOI: 10.1021/jm3006146 BindingDB Entry DOI: 10.7270/Q28G8MT5
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	1.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					Assay Description Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cells after 30 mins				J Med Chem 55: 8588-602 (2012) Article DOI: 10.1021/jm3006146 BindingDB Entry DOI: 10.7270/Q28G8MT5
UMR7200 CNRS/Universit£ de Strasbourg Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	3.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co., Ltd. Curated by PDSP K_i Database									J Pharmacol Exp Ther 282: 301-8 (1997) BindingDB Entry DOI: 10.7270/Q25T3J1N
					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Sus scrofa)	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested for the inhibition to V2 subtype receptor using [3H]- (VS2) as radioligand at 3 nM and arginine-vasopressin at 2 microM in LLCPKI cells				Bioorg Med Chem Lett 7: 719-724 (1997) Article DOI: 10.1016/S0960-894X(97)00050-4 BindingDB Entry DOI: 10.7270/Q2QC03HW
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
The College of New Jersey Curated by ChEMBL					Assay Description Binding affinity to vasopression V2 receptor (unknown origin) on isolated cell membrane by vasopression-self competition binding assay				Bioorg Med Chem Lett 23: 989-95 (2013) Article DOI: 10.1016/j.bmcl.2012.12.041 BindingDB Entry DOI: 10.7270/Q2Q52QZV
The College of New Jersey Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
Ferring B.V. US Patent					Assay Description Agonist activity of compounds on the human V2 receptor (h V2R) was determined in a transcriptional reporter gene assay by transiently transfecting an...				US Patent US10131692 (2018) BindingDB Entry DOI: 10.7270/Q2WQ05TR
Ferring B.V. US Patent					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Rattus norvegicus (Rat))	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
Albert Szent-Gy£rgyi Medical University Curated by ChEMBL					Assay Description Compound was evaluated for its dissociation constant (Kd) to rat kidney Vasopressin V2 receptor				Bioorg Med Chem Lett 9: 667-72 (1999) BindingDB Entry DOI: 10.7270/Q2QC040K
Albert Szent-Gy£rgyi Medical University Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (BOVINE)	BDBM35667 (AVP \| CHEMBL373742 \| US10131692, 44 (AVP) \| [3H]Ar...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
Max-Planck-Institut f£r Biophysik Curated by ChEMBL					Assay Description Inhibition of radioligand [3H]AVP binding to V2 receptor in bovine kidney inner medulla membrane				J Med Chem 37: 255-9 (1994) BindingDB Entry DOI: 10.7270/Q2H995TM
Max-Planck-Institut f£r Biophysik Curated by ChEMBL					More data for this Ligand-Target Pair