Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Voltage-dependent L-type calcium channel subunit alpha-1S' and Ligand = 'BDBM50227967'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1S (Rattus norvegicus)	BDBM50227967 (CHEMBL78973) Show SMILES CC(C)OC(=O)C1=C(C)N=C(C)N(C1c1ccccc1[N+]([O-])=O)C(=O)OCCN(Cc1ccccc1)Cc1ccc(Cl)c(Cl)c1 |c:6,t:9| Show InChI InChI=1S/C33H34Cl2N4O6/c1-21(2)45-32(40)30-22(3)36-23(4)38(31(30)26-12-8-9-13-29(26)39(42)43)33(41)44-17-16-37(19-24-10-6-5-7-11-24)20-25-14-15-27(34)28(35)18-25/h5-15,18,21,31H,16-17,19-20H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of [3H]- Nitrendipine binding to L-type calcium channels of rat cerebral cortex				J Med Chem 32: 2399-406 (1989) BindingDB Entry DOI: 10.7270/Q2GH9M57
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