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Found 1 hit Enz. Inhib. hit(s) with Target = 'WD repeat-containing protein 48' and Ligand = 'BDBM352012'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 48


(Homo sapiens (Human))		BDBM352012
PNG
(US9802904, 73)
Show SMILES CC(C)c1ccccc1-c1ncc(C)c(NCc2ccc(cc2)-c2ccnc(c2)C(F)(F)F)n1
Show InChI InChI=1S/C27H25F3N4/c1-17(2)22-6-4-5-7-23(22)26-32-15-18(3)25(34-26)33-16-19-8-10-20(11-9-19)21-12-13-31-24(14-21)27(28,29)30/h4-15,17H,16H2,1-3H3,(H,32,33,34)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 320n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of human USP1/UAF1 using Ub-AMC substrate by fluorescence assay

J Med Chem 57: 8099-110 (2014)


Article DOI: 10.1021/jm5010495
BindingDB Entry DOI: 10.7270/Q24X5BSH
More data for this
Ligand-Target Pair