Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a |
Ontario Institute for Cancer Research Curated by ChEMBL | Assay Description Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona... | J Med Chem 59: 2478-96 (2016) Article DOI: 10.1021/acs.jmedchem.5b01630 BindingDB Entry DOI: 10.7270/Q2VT1V0C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Binding affinity to His-tagged human WDR5 expressed in Escherichia coli BL21 by isothermal titration calorimetry | Eur J Med Chem 118: 1-8 (2016) Article DOI: 10.1016/j.ejmech.2016.04.032 BindingDB Entry DOI: 10.7270/Q26H4KBP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00195 BindingDB Entry DOI: 10.7270/Q2JQ153M | ||||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o... | Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o... | Citation and Details BindingDB Entry DOI: 10.7270/Q27W6GD6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
WD repeat-containing protein 5 (Homo sapiens (Human)) | BDBM50164794 (CHEMBL3798846 | US11174250, Example Table4.1.1 | U...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Exemplary compounds of the application were dissolved in 100% DMSO at 10 mM, assayed fresh, and then stored at −20° C. for repeat studies and o... | Citation and Details BindingDB Entry DOI: 10.7270/Q2C53Q0K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |