Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM173100'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173100 (US9096589, (S)-2-{2-[2-(5,7-Dimethyl-imidazo[1,2-a...) Show SMILES C[C@@H](CO)n1cc(nc1CCc1cn2c(C)cc(C)nc2n1)-c1cccs1 Show InChI InChI=1S/C20H23N5OS/c1-13-9-14(2)25-10-16(22-20(25)21-13)6-7-19-23-17(18-5-4-8-27-18)11-24(19)15(3)12-26/h4-5,8-11,15,26H,6-7,12H2,1-3H3/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
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