Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM173104'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM173104 (US9096589, 2-[2-(1-Cyclopentyl-4-thiophen-2-yl-1H-...) Show SMILES Cc1cc(C)n2cc(CCc3nc(cn3C3CCCC3)-c3cccs3)nc2n1 Show InChI InChI=1S/C22H25N5S/c1-15-12-16(2)26-13-17(24-22(26)23-15)9-10-21-25-19(20-8-5-11-28-20)14-27(21)18-6-3-4-7-18/h5,8,11-14,18H,3-4,6-7,9-10H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9096589 (2015) BindingDB Entry DOI: 10.7270/Q25Q4TTM
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