Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50334661'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50334661 (2,9-Dimethyl-5-((1-methyl-4-phenyl-1H-imidazol-2-y...) Show SMILES Cc1cc2c3cc(C)ccc3nc(CSc3nc(cn3C)-c3ccccc3)n2n1 Show InChI InChI=1S/C23H21N5S/c1-15-9-10-19-18(11-15)21-12-16(2)26-28(21)22(24-19)14-29-23-25-20(13-27(23)3)17-7-5-4-6-8-17/h4-13H,14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assay				Bioorg Med Chem 19: 642-9 (2011) Article DOI: 10.1016/j.bmc.2010.10.038 BindingDB Entry DOI: 10.7270/Q2TT4R73
					More data for this Ligand-Target Pair