Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha' and Ligand = 'BDBM4088'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM4088 (5-[(3,4-dichlorophenyl)methyl]-2,3,7,8-tetrahydrox...) Show SMILES Oc1ccc2c3cc(O)c(O)cc3n(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1O Show InChI InChI=1S/C20H13Cl2NO5/c21-12-3-1-9(5-13(12)22)8-23-14-7-17(26)16(25)6-11(14)10-2-4-15(24)19(27)18(10)20(23)28/h1-7,24-27H,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.10E+5	n/a	n/a	n/a	n/a	7.4	30
Pfizer					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of PKA activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] label...				J Med Chem 37: 2224-31 (1994) Article DOI: 10.1021/jm00040a015 BindingDB Entry DOI: 10.7270/Q27M0648
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