Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50045013'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50045013 (2-(2-Butoxy-phenyl)-3H-imidazo[4,5-b]pyridine | CH...) Show SMILES CCCCOc1ccccc1-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C16H17N3O/c1-2-3-11-20-14-9-5-4-7-12(14)15-18-13-8-6-10-17-16(13)19-15/h4-10H,2-3,11H2,1H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibition of PDE-IV isolated from guinea pig ventricle.				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
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