Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50304420'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50304420 (6-(3,4-Dimethoxyphenyl)-2-[4-(morpholinomethyl)ben...) Show SMILES COc1ccc(cc1OC)C1=NN(Cc2ccc(CN3CCOCC3)cc2)C(=O)CC1 |t:11| Show InChI InChI=1S/C24H29N3O4/c1-29-22-9-7-20(15-23(22)30-2)21-8-10-24(28)27(25-21)17-19-5-3-18(4-6-19)16-26-11-13-31-14-12-26/h3-7,9,15H,8,10-14,16-17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45.9	n/a	n/a	n/a	n/a	n/a	n/a
Kyoto 601-8550 Curated by ChEMBL					Assay Description Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysis				Bioorg Med Chem 17: 6959-70 (2009) Article DOI: 10.1016/j.bmc.2009.08.014 BindingDB Entry DOI: 10.7270/Q2WH2Q26
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