Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 7B' and Ligand = 'BDBM50272569'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 7B (Homo sapiens (Human))	BDBM50272569 (CHEMBL4128481) Show SMILES COc1ccc2c(N[C@@H](C)Cc3cc(C)[nH]n3)ncnc2c1OC |r| Show InChI InChI=1S/C17H21N5O2/c1-10(7-12-8-11(2)21-22-12)20-17-13-5-6-14(23-3)16(24-4)15(13)18-9-19-17/h5-6,8-10H,7H2,1-4H3,(H,21,22)(H,18,19,20)/t10-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc Curated by ChEMBL					Assay Description Inhibition of full length recombinant human PDE7B using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assay				J Med Chem 61: 4635-4640 (2018) Article DOI: 10.1021/acs.jmedchem.8b00374 BindingDB Entry DOI: 10.7270/Q2J67KDQ
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