Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase 2' and Ligand = 'BDBM65501'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase 2 (Homo sapiens (Human))	BDBM65501 (8-pCP-cGMP | Cyclic GMP analogs | cGMP) Show SMILES Nc1nc(=O)c2nc(Sc3ccc(Cl)cc3)n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c2[nH]1 Show InChI InChI=1S/C16H15ClN5O7PS/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(28-14)5-27-30(25,26)29-11/h1-4,8,10-11,14,23H,5H2,(H,25,26)(H3,18,20,21,24)/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	22	n/a	n/a	7.0	n/a
Baylor College of Medicine					Assay Description Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...				ACS Chem Biol 12: 2388-2398 (2017) Article DOI: 10.1021/acschembio.7b00369 BindingDB Entry DOI: 10.7270/Q2930RB1
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-dependent protein kinase 2 (Homo sapiens (Human))	BDBM65501 (8-pCP-cGMP | Cyclic GMP analogs | cGMP) Show SMILES Nc1nc(=O)c2nc(Sc3ccc(Cl)cc3)n([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)c2[nH]1 Show InChI InChI=1S/C16H15ClN5O7PS/c17-6-1-3-7(4-2-6)31-16-19-9-12(20-15(18)21-13(9)24)22(16)14-10(23)11-8(28-14)5-27-30(25,26)29-11/h1-4,8,10-11,14,23H,5H2,(H,25,26)(H3,18,20,21,24)/t8-,10-,11-,14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	257	n/a	n/a	7.0	n/a
Baylor College of Medicine					Assay Description Kinase activity was determined employing a microfluidic mobility-shift assay on a Caliper DeskTop Profiler (Caliper Life Sciences, PerkinElmer). The ...				ACS Chem Biol 12: 2388-2398 (2017) Article DOI: 10.1021/acschembio.7b00369 BindingDB Entry DOI: 10.7270/Q2930RB1
					More data for this Ligand-Target Pair				3D Structure (crystal)