Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50040376'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50040376 (1,3-Bis(cyclopropylmethyl)-8-bis[(phenylsulfonyl)a...) Show SMILES COc1ccc(Cn2c(nc3n(CC4CC4)c(=O)n(CC4CC4)c(=O)c23)N(S(=O)(=O)c2ccccc2)S(=O)(=O)c2ccccc2)cc1 Show InChI InChI=1S/C33H33N5O7S2/c1-45-26-18-16-25(17-19-26)20-35-29-30(36(21-23-12-13-23)33(40)37(31(29)39)22-24-14-15-24)34-32(35)38(46(41,42)27-8-4-2-5-9-27)47(43,44)28-10-6-3-7-11-28/h2-11,16-19,23-24H,12-15,20-22H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Concentration required to inhibit 50% activity of phosphodiesterase VA isoenzyme at 100 microM.				J Med Chem 37: 476-85 (1994) BindingDB Entry DOI: 10.7270/Q2P26X6N
					More data for this Ligand-Target Pair