Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50052081'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50052081 (CHEMBL91064 | [3-Hydroxymethyl-1-(3-methanesulfony...) Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(c3)S(C)(=O)=O)c2cc1OC Show InChI InChI=1S/C23H26O8S/c1-28-18-7-13-6-15(11-24)17(12-25)22(16(13)10-19(18)29-2)14-8-20(30-3)23(31-4)21(9-14)32(5,26)27/h6-10,24-25H,11-12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tan£be Seiyaku Company, Ltd. Curated by ChEMBL					Assay Description Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung				J Med Chem 39: 2696-704 (1996) Article DOI: 10.1021/jm9509096 BindingDB Entry DOI: 10.7270/Q2WS8TW7
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