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Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50052084'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50052084
PNG
(CHEMBL92043 | N-[5-(2,3-Bis-hydroxymethyl-6,7-dime...)
Show SMILES COc1cc2cc(CO)c(CO)c(-c3cc(NC(C)=O)c(OC)c(OC)c3)c2cc1OC
Show InChI InChI=1S/C24H27NO7/c1-13(28)25-19-7-15(9-22(31-4)24(19)32-5)23-17-10-21(30-3)20(29-2)8-14(17)6-16(11-26)18(23)12-27/h6-10,26-27H,11-12H2,1-5H3,(H,25,28)
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n/an/a 1.00E+5n/an/an/an/an/an/a



Tan£be Seiyaku Company, Ltd.

Curated by ChEMBL


Assay Description
Inhibition in vitro of Phosphodiesterase 5 isolated from guinea pig lung

J Med Chem 39: 2696-704 (1996)


Article DOI: 10.1021/jm9509096
BindingDB Entry DOI: 10.7270/Q2WS8TW7
More data for this
Ligand-Target Pair