Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50207129'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50207129 (3-(3,4-dimethoxybenzyl)-8-((6,7-dimethoxyisoquinol...) Show SMILES COc1ccc(Cn2c3nc(Cc4cncc5cc(OC)c(OC)cc45)[nH]c3c(=O)n(C)c2=O)cc1OC Show InChI InChI=1S/C27H27N5O6/c1-31-26(33)24-25(32(27(31)34)14-15-6-7-19(35-2)20(8-15)36-3)30-23(29-24)10-17-13-28-12-16-9-21(37-4)22(38-5)11-18(16)17/h6-9,11-13H,10,14H2,1-5H3,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes of Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human platelet PDE5 by [3H]cGMP scintillation proximity assay				Bioorg Med Chem Lett 17: 2376-9 (2007) Article DOI: 10.1016/j.bmcl.2006.11.019 BindingDB Entry DOI: 10.7270/Q2X63NSC
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