BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'm7GpppX diphosphatase' and Ligand = 'BDBM50237219'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
m7GpppX diphosphatase


(Homo sapiens (Human))		BDBM50237219
PNG
(CHEMBL4093512)
Show SMILES Cc1cc(OCC2CCN(Cc3c(Cl)cccc3Cl)CC2)c2c(N)nc(N)nc2c1
Show InChI InChI=1S/C22H25Cl2N5O/c1-13-9-18-20(21(25)28-22(26)27-18)19(10-13)30-12-14-5-7-29(8-6-14)11-15-16(23)3-2-4-17(15)24/h2-4,9-10,14H,5-8,11-12H2,1H3,(H4,25,26,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 334n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of human DcpS assessed as increase in SMN2 promoter activity

J Med Chem 60: 3094-3108 (2017)


Article DOI: 10.1021/acs.jmedchem.7b00124
BindingDB Entry DOI: 10.7270/Q2251MG2
More data for this
Ligand-Target Pair