Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150906 ((E)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-3-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206025 (CHEBI:60782 | Fluprostenol) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206012 (CHEMBL3956817) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206020 (CHEMBL3982726) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50169551 (CHEMBL3805134) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50085911 (7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | PubMed | n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]-PGE-2 from human Prostaglandin E receptor EP3 expressed in CHO-KI cells | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50085910 ((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=50%) | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206014 (CHEMBL3914661) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206028 (CHEMBL3967903) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50610936 (ONO-AG-367 | Ono-ag-367) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206026 (CHEMBL3920347) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150898 ((Z)-8-{(2R,3S,4R)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 23 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50035622 ((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | n/a | 24.5 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206018 (CHEMBL3967855) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 28 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50169552 (CHEMBL3804978) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 32 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human FP receptor expressed in human Chem1 cells assessed as increase in intracellular calcium level by fluorescence based analys... | ACS Med Chem Lett 7: 306-11 (2016) Article DOI: 10.1021/acsmedchemlett.5b00455 BindingDB Entry DOI: 10.7270/Q2125VKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150899 ((E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydrox...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 34.4 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206024 (CHEMBL3933326) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 43 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150904 ((Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 57 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150900 ((Z)-8-{(2R,3S,4R)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 58 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50090133 ((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 64 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=75%) | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150892 ((Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(R)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206021 (CHEMBL3904644) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 73 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50035622 ((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | n/a | n/a | 79 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%) | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50090140 (7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 85 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Displacement of [3H]-PGF2-alpha from human FP-receptor expressed in CHO-KI cells | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50090136 ((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
Procter & Gamble Pharmaceuticals Curated by ChEMBL | Assay Description Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=150%) | Bioorg Med Chem Lett 10: 1519-22 (2000) BindingDB Entry DOI: 10.7270/Q28W3CJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206013 (CHEMBL3938300) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206023 (CHEMBL3976382) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150894 ((Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(R)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 187 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150901 ((Z)-8-{(2R,3S,4R)-2-[(E)-(S)-4-(3-Chloro-phenoxy)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 194 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150896 ((Z)-8-{(2R,3S,4R)-2-[(E)-(S)-4-(3-Chloro-phenoxy)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 249 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM35847 ((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 250 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human FP receptor expressed in human Chem1 cells assessed as increase in intracellular calcium level by fluorescence based analys... | ACS Med Chem Lett 7: 306-11 (2016) Article DOI: 10.1021/acsmedchemlett.5b00455 BindingDB Entry DOI: 10.7270/Q2125VKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150897 ((Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 252 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM62356 (US9422273, 12b) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | 270 | n/a | n/a | 7.4 | 37 |
ALLERGAN, INC. US Patent | Assay Description Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug... | US Patent US9422273 (2016) BindingDB Entry DOI: 10.7270/Q2DZ076K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM240747 (US9422273, 12e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 270 | n/a | n/a | 7.4 | 37 |
ALLERGAN, INC. US Patent | Assay Description Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug... | US Patent US9422273 (2016) BindingDB Entry DOI: 10.7270/Q2DZ076K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206022 (CHEMBL3947086) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150902 ((Z)-8-[(2R,3S,4R)-4-Hydroxy-2-((E)-(R)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 293 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM240744 (US9422273, 12a) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 350 | n/a | n/a | 7.4 | 37 |
ALLERGAN, INC. US Patent | Assay Description Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug... | US Patent US9422273 (2016) BindingDB Entry DOI: 10.7270/Q2DZ076K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM240746 (US9422273, 12d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 360 | n/a | n/a | 7.4 | 37 |
ALLERGAN, INC. US Patent | Assay Description Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug... | US Patent US9422273 (2016) BindingDB Entry DOI: 10.7270/Q2DZ076K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50169548 (CHEMBL3805176) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 380 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human FP receptor expressed in human Chem1 cells assessed as increase in intracellular calcium level by fluorescence based analys... | ACS Med Chem Lett 7: 306-11 (2016) Article DOI: 10.1021/acsmedchemlett.5b00455 BindingDB Entry DOI: 10.7270/Q2125VKG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM240745 (US9422273, 12c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 460 | n/a | n/a | 7.4 | 37 |
ALLERGAN, INC. US Patent | Assay Description Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug... | US Patent US9422273 (2016) BindingDB Entry DOI: 10.7270/Q2DZ076K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206017 (CHEMBL3916674) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150891 ((Z)-8-[(R)-4-Hydroxy-2-((1R,2S,4S)-3-hydroxy-4-phe...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 573 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206027 (CHEMBL3932636) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 640 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150893 ((Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(S)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 781 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206019 (CHEMBL3955821) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 880 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150905 ((Z)-8-{(2R,3S,4R)-4-Hydroxy-2-[(E)-(S)-3-hydroxy-4...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 899 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206015 (CHEMBL3984438) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50206016 (CHEMBL3889508) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL | Assay Description Agonist activity at human prostaglandin FP receptor expressed in CHO cells assessed as increase in intracellular calcium level by Fura 2-AM dye based... | ACS Med Chem Lett 8: 107-112 (2017) Article DOI: 10.1021/acsmedchemlett.6b00415 BindingDB Entry DOI: 10.7270/Q2R78H6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50150903 ((Z)-7-[(2R,3S,4R)-4-Hydroxy-2-((E)-(S)-3-hydroxy-o...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.38E+3 | n/a | n/a | n/a | n/a |
Alcon Research, Ltd Curated by ChEMBL | Assay Description Efficacy for stimulation of prostanoid FP receptor-linked phosphoinositide turnover in Swiss 3T3 mouse fibroblast cells | Bioorg Med Chem Lett 14: 4525-8 (2004) Article DOI: 10.1016/j.bmcl.2004.06.037 BindingDB Entry DOI: 10.7270/Q2513ZZS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin F2-alpha receptor (Homo sapiens (Human)) | BDBM50610935 (DE-126 | ONO-9054 | Ono-9054 | SEPETAPROST | STN-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | UniChem | n/a | n/a | n/a | n/a | 3.03E+3 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair |
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