Compile Data Set for Download or QSAR

Found 18 hits of ec50 for UniProtKB: P51114   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RNA-binding protein FXR1 (Human)	BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCOS(O)(=O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCOS(O)(=O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504302 (3α,7α,11β,23-tetrahydroxy-6α-e...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCOS(O)(=O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.5	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504304 (3α,7α,11β-rihydroxy-6α-ethyl-5...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCOS(=O)(=O)O[Na])[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504304 (3α,7α,11β-rihydroxy-6α-ethyl-5...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCOS(=O)(=O)O[Na])[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504304 (3α,7α,11β-rihydroxy-6α-ethyl-5...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCOS(=O)(=O)O[Na])[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504311 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504311 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504306 (US11034717, Compound B) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H](C(C)CCOS(O)(=O)=O)[C@@]3(C)CCC2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504310 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)Cc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504310 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)Cc4nc(=O)o[nH]4)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	42	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504309 (US11034717, Compound L1) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504309 (US11034717, Compound L1) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504305 (US11034717, Compound A) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCC(O)=O)[C@@]3(C)CCC2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504301 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCO)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504303 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CCCO)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	264	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504300 (3α,7α,11β-trihydroxy-6α-ethyl-...) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H]([C@H](C)CC(O)=O)[C@@]3(C)C[C@H](O)C2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	680	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair
RNA-binding protein FXR1 (Human)	BDBM504307 (US11034717, Compound C) Show SMILES CC[C@H]1[C@@H](O)C2C3CC[C@H](C(C)CC(C)C(O)=O)[C@@]3(C)C(O)CC2[C@@]2(C)CC[C@@H](O)C[C@@H]12 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.75E+5	n/a	n/a	n/a	n/a
TBA					Assay Description AlphaScreen was used with the aim of identifying novel modulators by taking advantage of the bimolecular interaction prevailing between FXR and the L...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MC935W
					More data for this Ligand-Target Pair