Compile Data Set for Download or QSAR

Found 5 hits of ki for UniProtKB: P49327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24988 (1-(3-hexyl-4-oxooxetan-2-yl)tridecan-2-yl 2-formam...) Show SMILES CCCCCCCCCCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(CC(C)C)NC=O Show InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	300	-9.25	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24984 ((5E)-1-(3,5-dimethylphenyl)-5-[(5-phenylfuran-2-yl...) Show SMILES Cc1cc(C)cc(c1)N1C(=O)NC(=O)C(=Cc2ccc(o2)-c2ccccc2)C1=O |w:15.16| Show InChI InChI=1S/C23H18N2O4/c1-14-10-15(2)12-17(11-14)25-22(27)19(21(26)24-23(25)28)13-18-8-9-20(29-18)16-6-4-3-5-7-16/h3-13H,1-2H3,(H,24,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	380	-9.10	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24987 ((5E)-1-benzyl-5-{[5-(2-chlorophenyl)furan-2-yl]met...) Show SMILES Clc1ccccc1-c1ccc(\C=C2/C(=O)NC(=O)N(Cc3ccccc3)C2=O)o1 Show InChI InChI=1S/C22H15ClN2O4/c23-18-9-5-4-8-16(18)19-11-10-15(29-19)12-17-20(26)24-22(28)25(21(17)27)13-14-6-2-1-3-7-14/h1-12H,13H2,(H,24,26,28)/b17-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	850	-8.61	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24986 ((5E)-1-(3-bromophenyl)-5-{[5-(2-nitrophenyl)furan-...) Show SMILES [O-][N+](=O)c1ccccc1-c1ccc(C=C2C(=O)NC(=O)N(C2=O)c2cccc(Br)c2)o1 |w:13.13| Show InChI InChI=1S/C21H12BrN3O6/c22-12-4-3-5-13(10-12)24-20(27)16(19(26)23-21(24)28)11-14-8-9-18(31-14)15-6-1-2-7-17(15)25(29)30/h1-11H,(H,23,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	880	-8.59	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair
Fatty acid synthase [2202-2509] (Homo sapiens (Human))	BDBM24985 ((5E)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}...) Show SMILES Cc1ccccc1N1C(=O)NC(=O)C(=Cc2ccc(o2)-c2ccc(F)cc2)C1=O |w:14.15| Show InChI InChI=1S/C22H15FN2O4/c1-13-4-2-3-5-18(13)25-21(27)17(20(26)24-22(25)28)12-16-10-11-19(29-16)14-6-8-15(23)9-7-14/h2-12H,1H3,(H,24,26,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	910	-8.57	n/a	n/a	n/a	n/a	n/a	7.5	37
Burnham Institute for Medical Research					Assay Description The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...				Mol Cancer Ther 6: 2120-6 (2007) Article DOI: 10.1158/1535-7163.MCT-07-0187 BindingDB Entry DOI: 10.7270/Q2F769V8
					More data for this Ligand-Target Pair