Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against wild type EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0380 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against E203Q,D204N,D206N,E209Q EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against E203Q,D204N,D206N EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50001714 (2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0500 | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Dissociation constant against D216N,D217N,E218Q EL-2 Opioid receptor kappa 1 expressed in HEK cells | J Med Chem 43: 1251-2 (2001) BindingDB Entry DOI: 10.7270/Q270824F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021328 (3-Cyclopropylmethyl-11-ethyl-8-hydroxy-6-methyl-3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM21130 (N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center Curated by ChEMBL | Assay Description Binding affinity to rat kappa opioid receptor expressed in HEK293 cell membranes | Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50000788 ((morphine)4-methyl-(1S,5R,13R,14S,17R)-12-oxa-4-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd. Curated by ChEMBL | Assay Description Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the... | Bioorg Med Chem Lett 10: 831-4 (2000) BindingDB Entry DOI: 10.7270/Q2N29XG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021324 (3-(1-Cyclopropylmethyl-3-methyl-piperidin-3-yl)-ph...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021323 (3-(1-Allyl-3-methyl-piperidin-3-yl)-phenol | 3-(1-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021322 (3-(3-Methyl-1-phenethyl-piperidin-3-yl)-phenol | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM21025 ((2R)-2-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50021327 (3-(1,3-Dimethyl-piperidin-3-yl)-phenol | 3-(1,3-Di...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Opioid receptor affinity against Opioid receptor kappa 1 by using the curve-fitting program LIGAND | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50452273 (Dihydromorphine) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated for Opioid receptor kappa 1 affinity against the receptor site model site 4(kappa) | J Med Chem 29: 531-7 (1986) BindingDB Entry DOI: 10.7270/Q2WH2QKX | |||||||||||
More data for this Ligand-Target Pair |